Final answer:
The drug of choice for an infection caused by non-penicillinase-producing Staphylococcus is penicillin V, as these strains do not deactivate the antibiotic. Other drugs such as vancomycin are reserved for more resistant infections. Antibiotic sensitivity testing is crucial for appropriate treatment choice.
Step-by-step explanation:
In an infection caused by non-penicillinase-producing Staphylococcus, the drug of choice is penicillin V. This is because non-penicillinase-producing strains do not have the enzyme that deactivates the penicillin, making penicillin V an effective form of treatment. While other antibiotics such as tetracycline, clindamycin, and vancomycin are used to treat resistant forms of Staphylococcus infections such as MRSA, for non-penicillinase-producing Staphylococcus, penicillin V is typically sufficient unless antibiotic sensitivity tests suggest otherwise.
It is critical to use antibiotic sensitivity to identify the most suitable antibiotic due to the emergence of resistant strains of bacteria like MRSA. Still, traditional antibiotics like penicillin remain effective against non-resistant strains. Additionally, while vancomycin is effective against gram-positive organisms, it is typically reserved for treating more resistant infections and is considered one of the last lines of defense.