Final answer:
Angled Class II, division 1 malocclusion is differentiated from division 2 by the inclination of maxillary incisors, with division 1 having protruded incisors and division 2 having retroclined incisors.
Step-by-step explanation:
An Angle Class II, division 1 malocclusion can be differentiated from an Angle Class II, division 2 malocclusion based upon the inclination of maxillary incisors. In Class II, division 1, the maxillary incisors are usually protruded, while in Class II, division 2, the maxillary incisors are often retroclined or tipped backward. This is an observation that can be made by examining the orientation of the upper front teeth. Other aspects like molar relationship, severity, overbite, or crowding, while important for a full diagnosis, are not the differentiating factors between these two specific divisions.