Question

18B-55 Anaphylaxis:

A. can be ruled out if serum tryptase not elevated
B. can occur on first exposure to drug
C. type ii IgE mediated
D. ?
E. mediated primarily by basophils

Answer 1

Anaphylaxis is a type I hypersensitivity reaction that can occur on first exposure to an allergen. It is mediated by IgE antibodies and mast cell degranulation, which release chemical mediators that elicit the allergic response.

Step-by-step explanation:

Anaphylaxis is a type I hypersensitivity reaction that can occur on first exposure to an allergen. It is a systemic reaction and can be life-threatening. It is mediated by IgE antibodies and mast cell degranulation, which release chemical mediators that elicit the allergic response.

Serum tryptase levels can be used to confirm a diagnosis of anaphylaxis, but their absence does not rule out anaphylaxis.

Basophils, another type of white blood cell, are also involved in the immune response, but mast cells are primarily responsible for mediating anaphylaxis.