Question

Which drugs are affected by plasma cholinesterase deficiency

A. Mivacurium, procaine
B. Other combo that weren't C. Remifentanil, suxamethonium
D. Rocuronium, vecuronium
E. Ondansetron, lignocaine

Answer 1

Mivacurium and Suxamethonium are significantly affected by plasma cholinesterase deficiency, resulting in prolonged action of these drugs.

Step-by-step explanation:

The drugs affected by plasma cholinesterase deficiency are Mivacurium and Suxamethonium (also known as succinylcholine). Plasma cholinesterase, also known as pseudocholinesterase, is an enzyme that is responsible for the hydrolysis of several compounds, including the breakdown of certain muscle relaxants used during anesthesia, such as mivacurium and suxamethonium. A deficiency in this enzyme leads to a prolonged duration of action of these drugs, as their breakdown in the plasma is significantly slower, potentially causing prolonged respiratory muscle paralysis after surgery.