Final Answer:
Contraindicated in heart failure due to negative inotropic effects,thus the correct option is (D).
Step-by-step explanation:
Beta blockers, such as 18B-98, exert their therapeutic effects by blocking the action of beta-adrenergic receptors. In the context of heart failure, beta blockers are contraindicated due to their negative inotropic effects on the heart. Inotropic refers to the force of muscle contraction, and negative inotropic effects mean that these medications reduce the force of contraction of the heart muscle,thus the correct option is (D).
The heart's ability to pump blood effectively is crucial, especially in conditions like heart failure where the heart is already weakened. Beta blockers can further compromise this function by inhibiting the sympathetic nervous system's influence on the heart, resulting in a reduction in heart rate and contractility. This diminished contractility is detrimental in heart failure patients who rely on optimal heart function to maintain adequate cardiac output.
Choosing beta blockers for heart failure patients would exacerbate their condition rather than alleviate it. Therefore, the use of 18B-98, or any beta blocker, is not recommended in heart failure cases due to their negative inotropic effects, which can worsen the patient's cardiovascular status. It's essential for healthcare providers to consider these pharmacological nuances to ensure the safety and efficacy of the chosen treatment regimen for individuals with heart failure.