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18B-34 Side effects of chemotherapy:

A. Anthracyclines such as daunorubicun and doxorubin can cause acute myocarditis
B. anthracyclines such as daunorubicin and doxorubin can cause chronic dilated cardiomyopathy
C. bone marrow suppression does not inhibit platelet ?production
D. pulmonary oxygen toxicity following bleomycin is a life-long phenomenon
E. vincristine causes both peripheral and autonomic neuropathy

User Indi
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Final answer:

Anthracyclines like daunorubicin and doxorubicin can cause heart damage, chemotherapy causes bone marrow suppression including reduced platelet production, bleomycin-induced pulmonary toxicity is reversible, and vincristine can cause peripheral and autonomic neuropathy.

Step-by-step explanation:

The side effects of chemotherapy are numerous due to the drugs' non-specific action on rapidly dividing cells, not just cancer cells but also healthy cells. Anthracyclines such as daunorubicin and doxorubicin can cause serious cardiac complications. Specifically, daunorubicin and doxorubicin are known to potentially cause acute myocarditis and chronic dilated cardiomyopathy. Additionally, one of the common side effects of chemotherapy, including drugs like cyclophosphamide, is bone marrow suppression, which does inhibit platelet production. This can lead to a reduction in white blood cell count, including a reduction in neutrophils (neutropenia), which are essential for fighting infections. Another chemotherapeutic agent, bleomycin, can cause pulmonary oxygen toxicity, but this is typically a reversible side effect once the treatment is discontinued, and not a lifelong phenomenon. Lastly, vincristine can cause both peripheral and autonomic neuropathy, leading to a variety of symptoms including numbness, tingling, and autonomic dysfunction.

User Raphy
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