Final answer:
Paracetamol, or Acetaminophen, is an analgesic and antipyretic with only weak anti-inflammatory properties that is safer for people with gastric issues. The maximum recommended adult daily dose is 4000mg, and it is typically not associated with gastric irritation.
Step-by-step explanation:
The student is inquiring about the medicinal properties and safety profile of Paracetamol, also known as Acetaminophen in the United States.
- Paracetamol has analgesic and antipyretic effects but is only weakly anti-inflammatory, unlike its NSAID (nonsteroidal anti-inflammatory drug) counterparts like aspirin.
- Paracetamol is metabolized to benzoquinoneimine, a toxic intermediate, which is inactivated by conjugation with glutathione. In cases of overdose where glutathione stores are depleted, liver damage can occur.
- It is recommended that the daily dose of Paracetamol should not exceed 4000mg for an adult to avoid potential hepatoxicity.
- Gastric irritation is not commonly associated with Paracetamol usage, making it a preferable analgesic for patients with gastric issues or those who require a medication with less risk of gastrointestinal side effects.