Question

18A-106 1st generation Histamine 1 antagonists do not cause

A. Antiemetic
B. Anticholinergic
C. Extrapyramidal
D. ?
E. ?

Answer 1

Antihistamines prevent mast cells from releasing histamines and causing allergy symptoms by binding to histamine receptors.

Step-by-step explanation:

Antihistamines are medications that prevent mast cells from releasing histamines, which are responsible for allergy symptoms. They work by binding to histamine receptors in various parts of the body, including the nose, skin, and inner ear. There are two types of antihistamines: H1-antihistamines and H2-antihistamines. H1-antihistamines specifically target histamine H1 receptors and are used to treat allergic reactions, while H2-antihistamines target histamine H2 receptors and are used to treat gastric acid conditions.

Answer 2

First generation Histamines 1 antagonists do not cause extrapyramidal (Option C).

Step-by-step explanation:

The 1st generation H1 antagonist antihistamines do not cause, such as Cyproheptadine and diphenhydramine, are known for their multiple effects beyond their primary purpose of blocking H1 receptors.

For instance, in addition to their antihistaminic effects, they are also known for their antiemetic and sedative properties due to their ability to cross the blood-brain barrier. Moreover, they exhibit anticholinergic effects, which may lead to symptoms like dry mouth, blurred vision, constipation, and urinary retention.

However, one effect that 1st generation antihistamines do not cause is extrapyramidal symptoms. Extrapyramidal symptoms are typically associated with drugs that affect the dopamine system in the brain, such as certain antipsychotics.

Since 1st generation H1 antagonist antihistamines do not generally impact dopamine systems substantially, they are not associated with causing extrapyramidal symptoms, which include movement disorders and tremors. It's crucial to differentiate these side effects when discussing and prescribing antihistamine medications.

Thus, the correct option is C.

Your question is incomplete but most probably your full question was

1st generation Histamine 1 antagonists do not cause

A. Antiemetic

B. Anticholinergic

C. Extrapyramidal

D. Cyproheptadine

E. Diphenhydramine