Final answer:
The most suitable device for preventing seroma in a post-mastectomy patient is a closed suction drainage system made of polypropylene, as it effectively removes fluids while reducing the risk of infection.
Step-by-step explanation:
The most appropriate device to use for a 67-year-old lady who undergoes a mastectomy and axillary node clearance for breast cancer to prevent the development of a seroma is a closed suction drainage system made of polypropylene. Closed suction drainage systems are effective in removing fluids that may accumulate in the surgical area, reducing the risk of seroma formation. This type of system is preferred over passive options because it provides consistent negative pressure, which promotes fluid removal and can reduce the risk of infection. Materials like polypropylene are typically used as they are less reactive than latex, which some patients may be allergic to. Penrose drains are less commonly used in such settings due to a higher risk of infection, and VAC wound closure systems are generally applied for complex or open wounds that require assistance in closure and healing, which may not be suitable in this scenario.