Final answer:
The two worst risks for a patient on fibrates are an increased risk of stroke or heart attack, and gall bladder disease, due to potential clot formation and changes in bile composition, respectively.
Step-by-step explanation:
Fibrates are a class of medication primarily used to treat abnormal blood lipid levels, specifically to reduce triglycerides and increase HDL cholesterol. While effective in their function, patients taking fibrates are at risk of experiencing several side effects. In terms of the most serious risks, the two worst things a patient is at risk of developing when on a fibrate are increased risk of stroke or heart attack, and gall bladder disease.The risk of a heart attack or stroke is of particular concern as fibrates can potentially induce clot formation. On the other hand, gall bladder disease can be prompted by alterations in bile composition that fibrates may cause, leading to gallstone formation and consequent gall bladder complications.