Final answer:
Gallbladder disease manifests through gallstones, jaundice, and abdominal symptoms.
Step-by-step explanation:
The three main manifestations of gallbladder disease are gallstones, jaundice, and abdominal symptoms.
Gallstones are solid particles that form when a large amount of cholesterol accumulates in the gallbladder. These stones can block the bile duct and cause pain.
Jaundice occurs when a gallstone blocks the bile duct, preventing the bile pigment from being excreted. This leads to a yellow coloration of the skin and whiteness of the eyes.
Other abdominal symptoms, such as fever, malaise, and anemia, may also be present in gallbladder disease.