Final answer:
Ezetimibe is used to lower cholesterol levels, particularly low-density lipoprotein (LDL), which is often referred to as 'bad cholesterol'. Its primary function is to decrease cholesterol absorption in the intestine, and it can be more effective when used in combination with statins.
Step-by-step explanation:
Ezetimibe is a medication used to manage hyperlipidemia, which includes various conditions that result in higher than normal lipid levels in the blood. Specifically, ezetimibe works by reducing the cholesterol absorption in the small intestine, leading to a decrease in the total cholesterol and low-density lipoprotein (LDL), commonly known as "bad cholesterol". It is particularly effective when combined with statins, another class of cholesterol-lowering drugs. While statins primarily function by inhibiting the enzyme HMG-CoA reductase to reduce cholesterol synthesis in the body, ezetimibe complements this action by targeting cholesterol uptake. This dual approach can be more effective in lowering LDL cholesterol levels, thereby reducing the risk of atherosclerosis and related cardiovascular diseases. However, it is important to use this combination therapy under close supervision due to the increased risk of side effects such as myopathy and rhabdomyolysis.