Question

What does pancreatic lipase from the intestine cleave triacylglycerols into?

A)1-monoacyl glycerol + 2 FA
B)2-monoacyl glycerol + 2 FA
C)2-monoacyl glycerol + 3 FA
D)1-monoacyl glycerol + 3 FA

Answer 1

Pancreatic lipase breaks down triacylglycerols into 2-monoacylglycerol and two free fatty acids, which are then absorbed and transported as chylomicrons through the lymphatic and circulatory systems.

Step-by-step explanation:

Pancreatic lipase from the intestine cleaves triacylglycerols into 2-monoacylglycerol and two free fatty acids (FA). This is a key step in the digestion of fats. When triglycerides enter the small intestine, they are emulsified by bile salts, which disperses them into smaller droplets, enhancing the accessibility for pancreatic lipases. These enzymes then break down the triglycerides into 2-monoacylglycerol and free fatty acids, which can be absorbed across the intestinal membrane. Inside the intestinal cells, these molecules can be reassembled into new triglycerides and then packaged into chylomicrons for transport through the lymphatic and circulatory systems as part of lipid metabolism.