Final answer:
Pruriceptive pruritus is a type of itch that arises from abnormalities in the skin, often induced by inflammatory skin diseases or external stimuli, activating peripheral nerve fibers responsible for the sensation of itch.
Step-by-step explanation:
What is Pruriceptive Pruritus?
Pruriceptive pruritus refers to itching that arises from abnormalities in the skin itself. This type of pruritus is often caused by skin diseases such as eczema, dermatitis, or infections. It is one of the different classifications of pruritus, with others including neuropathic, neurogenic, and psychogenic pruritus. In pruriceptive pruritus, the peripheral sensory nerve fibers (C-fibers) in the skin are activated either by endogenous or exogenous stimuli. These stimuli can be due to inflammatory processes, mechanical stimuli, or chemical substances applied to or released within the skin. This leads to the sensation of itch that prompts an urge to scratch. Scratching can provide temporary relief, but it can also damage the skin barrier, potentially leading to further inflammation and a cycle of worsening itch and skin damage.