Final answer:
Neuropathic pruritus refers to itching caused by nerve dysfunction. Various stimuli can stimulate nerves to cause itching, including physical and chemical factors. Treating neuropathic pruritus involves addressing the underlying cause and managing symptoms.
Step-by-step explanation:
Neuropathic pruritus refers to itching that is caused by nerve dysfunction. It is characterized by a chronic itch sensation that can be triggered by various stimuli. These stimuli may include physical factors like heat, pressure, or touch, as well as chemical factors like certain medications or substances.
When nerves are stimulated to cause itching, it is often due to the release of certain chemical mediators, such as histamine. Histamine can be released in response to an allergic reaction or inflammation, which can trigger itchiness. Additionally, substances like prostaglandins and cytokines can also contribute to nerve stimulation and itching.
Treating neuropathic pruritus involves addressing the underlying cause of the nerve dysfunction and managing the symptoms. This may include medications that target nerve activity or reduce inflammation, as well as lifestyle modifications to minimize triggers and promote skin health.