Final answer:
In cats with Ehlers-Danlos syndrome, the characteristic of skin fragility is due to a deficiency in type-III collagen, causing the skin to be very fragile and easily damaged from minor impacts.
Step-by-step explanation:
The characteristic of skin fragility in cats with Ehlers-Danlos syndrome (EDS) is primarily due to a deficiency in type-III collagen. This deficiency can be the result of mutations in the collagen synthesis process or a lack of the enzyme hydroxylase. In the case of the integumentary system, EDS affects the skin's strength and elasticity, leading to symptoms such as easy bruising, skin that is easily damaged from minor friction or trauma, and slow wound healing due to the compromised structure of collagen fibers.
Collagen diseases like EDS are a result of progressive deterioration of collagens, which have wide-reaching implications throughout the body. Aside from the skin and vascular problems, other complications may involve joints, heart valves, organ walls, and arterial walls. However, when it comes to cats with EDS, the most notable symptom is their extremely fragile skin. This can be a significant concern for veterinarians and pet owners alike, as normal handling or minor accidents can cause severe skin injuries.