Final answer:
Ehlers-Danlos syndrome, also known as cutaneous asthenia, is a collagen disease that affects both humans and animals and is characterized by fragile skin and joint issues. Animals with this condition may experience progressive deterioration of collagen, leading to skin and vascular problems. Management of the condition in animals depends on the severity of the symptoms and may range from lifestyle adjustments to intensive supportive care.
Step-by-step explanation:
Ehlers-Danlos syndrome (EDS), also known as cutaneous asthenia or dermatosparaxis, is a group of collagen diseases that can affect both humans and animals. In animals, this condition is often caused by a deficiency in type-III collagen, due to a lack of the enzyme hydroxylase or mutations in the amino acid sequences during collagen synthesis. Collagen is a crucial part of the extracellular matrix (ECM) that provides strength and elasticity to the skin, among other tissues.
Animals with EDS may have hyperextensible skin, fragility, and poor wound healing due to the progressive deterioration of collagens. This can lead to severe skin and vascular problems, which are the major symptoms. While humans with Ehlers-Danlos syndrome may manage their condition with medical care and lifestyle adjustments, animals cope differently depending on the severity of their symptoms. Animals with mild cases might live relatively normal lives with some care adjustments, but those with severe symptoms may require more intensive management.
It's also essential for affected animals to avoid unnecessary stress or injury to the skin, as their capacity to heal is compromised. Additionally, supportive care such as wound management and the use of soft bedding can help minimize the impact of the syndrome. Breeding practices may also be adapted to reduce the prevalence of this genetic disorder.