Final answer:
Ehlers-Danlos syndrome (EDS) is a genetic disorder that affects the skin, joints, and blood vessels due to collagen defects. Individuals with EDS experience symptoms like flexible joints, stretchy skin, and easy bruising. It can lead to serious complications such as heart valve problems or arterial rupture.
Step-by-step explanation:
Ehlers-Danlos Syndrome (EDS)
Ehlers-Danlos syndrome (EDS) is a group of genetic disorders that primarily affect the skin, joints, and blood vessels. It is caused by defects in the collagen protein, which is crucial for providing strength and elasticity to connective tissue. People with EDS typically have overly flexible joints, stretchy skin, and a tendency to bruise easily. Due to its genetic nature, the syndrome often runs in families.
The condition manifests in various forms, each with a potential deficiency of different types of collagen or related anomalies. For instance, a deficiency in type-III collagen may result from genetic mutations or issues with the enzyme hydroxylase, leading to progressive deterioration of collagen. This can impact various parts of the body, including the heart, arterial walls, and organ walls, resulting in complications such as heart valve problems or a risk of arterial rupture. Skin and vascular issues are prominent symptoms of EDS, making it a significant concern within dermatological and systemic health contexts.