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Asphyxia / Hypoxic Acidemia

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Asphyxia, also known as hypoxic acidemia, is a state where the body does not receive enough oxygen, leading to acid-base imbalance such as respiratory acidosis or metabolic acidosis. These conditions are due to excessive carbonic acid from CO₂ buildup or metabolic issues leading to acids accumulation. It results in severe symptoms and can be caused by respiratory problems, organ failure, or metabolic disorders.

Step-by-step explanation:

Understanding Asphyxia and Hypoxic Acidemia

Asphyxia, or hypoxic acidemia, is a condition characterized by insufficient oxygen supply to the body that can lead to various symptoms including possible cherry-red skin, cyanosis, confusion, nausea, gasping for air, seizures, and ultimately metabolic acidosis. Respiratory acidosis occurs when there is excessive carbonic acid in the blood due to an accumulation of CO₂, which can result from respiratory complications like pneumonia and congestive heart failure. In contrast, respiratory alkalosis involves a deficiency in carbonic acid and CO₂ levels, often due to hyperventilation caused by factors such as emotional distress, fever, or infections. Conditions like diabetic ketoacidosis, kidney failure, and liver failure can lead to metabolic acidosis, exacerbating the acid-base imbalance in the body.

Metabolic Acidosis and Homeostasis

Metabolic acidosis involves an accumulation of acids in the body fluids, potentially due to conditions reducing the effectiveness of breathing or disorders affecting metabolic processes. Infamous examples include diabetic ketoacidosis from poorly managed diabetes and acidosis resulting from severe diarrhea or organ failures like kidney and liver dysfunction. The disruption of acid-base homeostasis leads to severe health implications including labored breathing, dehydration, and reduced oxygen transport by hemoglobin.

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