Final answer:
It is false that fluid shifts from interstitial fluid into the blood when the sum of blood hydrostatic pressure and interstitial fluid colloid osmotic pressure exceeds the sum of interstitial fluid hydrostatic pressure and blood colloid osmotic pressure; as these conditions actually cause fluid to move out of the capillaries.
Step-by-step explanation:
The question refers to the process by which fluid moves between the blood in the capillaries and the interstitial fluid in tissue spaces.
It is incorrect to say that fluid shifts out of the interstitial fluid and into the blood when the sum of blood hydrostatic pressure (BHP) and interstitial fluid colloid osmotic pressure (IFCOP) is greater than the sum of interstitial fluid hydrostatic pressure (IFHP) and blood colloid osmotic pressure (BCOP).
In fact, the opposite is true; fluid will shift out of the blood and into the interstitial fluid. This is because BHP and IFCOP work to move fluid out of the capillaries, while IFHP and BCOP promote reabsorption, moving fluid back into the capillaries. Filtration occurs when the BHP is greater than BCOP, pushing fluid out of the capillaries.
Meanwhile, osmotic pressure, influenced by solute concentration gradients, is responsible for the reabsorption of fluid back into the capillaries.