Final answer:
Neanderthals were a distinct group in the genus Homo that inhabited Europe and Southwest Asia from approximately 30-125,000 years ago. They had distinct physical features and cultural practices.
Step-by-step explanation:
The distinct group in the genus Homo that inhabited Europe and Southwest Asia from approximately 30-125,000 years ago is Neanderthals. Neanderthals were a species of early humans who evolved from Homo erectus and lived in Europe and western Asia during the Pleistocene epoch. They had distinct physical features, such as a stocky build, prominent brow ridges, and rounded skulls, and they had well-developed tools and cultural practices.