Final answer:
Timbuktu, located in the Mali Empire, had the strongest trade connections with the Arabian peninsula.
Step-by-step explanation:
The medieval African city that had the strongest trade connections with the Arabian peninsula was Timbuktu.
Timbuktu, located in the Mali Empire, was a major center for trade in West Africa. It was a hub for the trans-Saharan trade route and had important connections with Arab traders from the Arabian peninsula. The city's strategic location made it a key trading post for goods such as gold, salt, textiles, ivory, and enslaved people.
Timbuktu's trade connections with the Arabian peninsula played a significant role in the economic and cultural development of the Mali Empire and facilitated the exchange of goods and ideas between Africa and the Arab world.