Answer: She was a successful diplomat despite her lack of education.
Explanation: Isabella d'Este was Marchioness of Mantua, and one of the most important women during the Italian Renaissance. She was a patron of the arts, culture, and fashion.
Isabella d'Este grew up in a cultured family in Ferrara and received a fine classical education, meeting many scholars and artists when young. She helped make Mantua a centre of art and learning. She also served as regent of Mantua during her husband's absense and the minority of her son. She was a successful diplomat, having convinced King Louis XII of France to not send his troops against Mantua.