Final answer:
Columbia used negotiation and intervention in Latin America as strategies to advance its expansion.
Step-by-step explanation:
Strategies employed by Columbia to further its expansion included negotiating with the United States for the construction of a canal across the Panama isthmus, granting the U.S. a lease on the land in exchange for payment and rental fees. However, the Colombian Senate rejected the treaty due to public outcry over perceived inadequate compensation. Additionally, Columbia practiced intervention in Latin America to maintain control over the northernmost region of Panama and deter independence movements. This involved seeking U.S. protection to prevent Panama from declaring independence.