Final answer:
In Hfr f- transfer, genes located far from the origin tend not to be transferred because the transfer process is too slow to reach distant genes.
Step-by-step explanation:
In Hfr f- transfer, genes located far from the origin tend not to be transferred because the transfer process is too slow to reach distant genes.
The timing of conjugation that leads to the transfer of genes from Hfr strains to F- cells is a refined process, and the time it takes to transfer a complete gene reflects the size (length) of the gene. Genes located closer to the integration site of the F plasmid are transferred more quickly and are more likely to be recombined into the recipient F- cell's chromosome.
Therefore, the correct answer is C. The transfer process is too slow to reach distant genes.