Final answer:
The Mona Lisa, created by Leonardo da Vinci, is the most famous work of Western art. It is renowned for its elusive smile and status as an icon of the Renaissance. The painting is a portrait of a merchant's wife but was never delivered to the patron.
Step-by-step explanation:
The most famous work of Western art, known as the Mona Lisa, was created by Leonardo da Vinci. This renowned painting is not only famous for its enigmatic smile but also because it represents a shift in the meaning of portraits during the Renaissance. The Mona Lisa, or La Gioconda, is thought to be a portrait of the wife of a Florentine merchant, however, it was never delivered to him. Leonardo da Vinci kept the painting with him until the end of his life, further adding to its mystery and allure. The smile on the Mona Lisa's face is particularly noteworthy due to the subtle shading around the corners of the mouth and eyes, which gives the smile an elusive quality. Leonardo's influence extends beyond his artistic achievements, as his work continues to guide and inspire individuals in various fields.