Question

What HLA class II component is digested by macrophages during antigen processing?

a) HLA-DP
b) HLA-DQ
c) HLA-DR
d) HLA-A

Answer 1

HLA-DR is the HLA class II component that is digested by macrophages during antigen processing.

Step-by-step explanation:

The HLA class II component that is digested by macrophages during antigen processing is HLA-DR. During antigen processing, macrophages phagocytose foreign antigens and then partially digest them in lysosomes. The resulting protein fragments are then embedded in HLA class II molecules, such as HLA-DR, and presented on the surface of the macrophage to activate helper T cells of the immune system.