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If one of your cells were 1000 times bigger than real life, how long would the genome (haploid) be?

User VSB
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Final answer:

The magnified haploid human genome would measure approximately 1000 meters in length. The DNA is compacted through supercoiling to fit into the small nucleus of a cell, allowing efficient organization and accessibility for gene expression.

Step-by-step explanation:

If one of your cells were to be magnified 1000 times larger than real life, the genome (haploid) which normally consists of about 3 billion base pairs (and measures approximately 1 meter when stretched out), would be equivalently magnified. This means that the haploid human genome would measure roughly 1000 meters in length under this magnification. This is an interesting way to conceptualize the complexity and size of the eukaryotic genomes, particularly the human genome which is tightly packaged within the cell's nucleus.

To fit such a large amount of DNA into a relatively small nucleus (of approximately 10 um in diameter), the DNA must be highly compacted and organized through a process called supercoiling. This process enables the extremely long DNA molecules to be wound and arranged in a way that they can fit inside the small space within a cell's nucleus, while still allowing parts of the DNA to be accessible for gene expression when needed. The comparison to a vastly magnified cell helps underline the efficiency of the cell's packing mechanisms.

User Ochi
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