Question

Charging of Transfer RNAs. How is the amino acid held on the charged tRNA?

A) Covalently bonded to the tRNA.
B) Non-covalently bonded to the tRNA.
C) It's not held on the tRNA.
D) Held by a separate protein molecule.

Answer 1

A charged tRNA is held non-covalently bonded to its amino acid through the process of tRNA charging, which involves the attachment of the correct amino acid to the tRNA molecule facilitated by aminoacyl tRNA synthetases. The amino acid is first activated by the addition of AMP and then transferred to the tRNA, making it charged.

Step-by-step explanation:

A charged tRNA is held non-covalently bonded to its amino acid. The process of tRNA charging involves the attachment of the correct amino acid to the tRNA molecule, which is facilitated by a group of enzymes called aminoacyl tRNA synthetases. These enzymes catalyze the formation of a high-energy bond between the amino acid and adenosine monophosphate (AMP). After the amino acid is transferred to the tRNA, making it charged, the AMP is released.