Final answer:
Lorenzo de Zavala was a Mexican politician who denounced Santa Anna, signed the Declaration of Independence, and became the first Vice President of Texas.
Step-by-step explanation:
The Mexican politician who denounced Santa Anna and his dictatorship, signed the Declaration of Independence, and became the first Vice President of Texas was Lorenzo de Zavala. Zavala was a prominent figure in the Texas Revolution and played a vital role in the fight for Texas independence from Mexico. His actions and leadership contributed to the establishment of the Republic of Texas.