Final answer:
The Mona Lisa was created by Leonardo da Vinci, a renowned polymath of the Renaissance era, who was also famous for his anatomical studies.
Step-by-step explanation:
The creator of the Mona Lisa, also known as La Gioconda, who was indeed a polymath and crafted detailed anatomical studies, is A) Leonardo da Vinci. Not only was he an iconic painter, but Leonardo da Vinci also delved into various fields such as architecture, science, mathematics, engineering, and more. His insatiable curiosity led him to acquire knowledge in these diverse areas, making him one of the most remarkable figures of the Renaissance period.