Final answer:
The correct answer to fill in the blank is 'enigmatic,' as it best describes the nature of 'hope' that is complex, mysterious, and puzzling, in line with the provided context.
Step-by-step explanation:
The line 'For that hope whose wanderings are so __________ is to many men a comfort, according to the Chorus' suggests a blank needing to be filled with a descriptor of 'hope's' nature. Based on the provided context that speaks to the mysteriousness and depth of human experiences and the existential questions they pose, the most fitting word to describe the nature of 'hope' in this phrase would be 'enigmatic'. The word 'enigmatic' suggests something that is mysterious, puzzling, or difficult to understand, which aligns with the complex and ambiguous nature of 'hope' that is suggested by the surrounding text.