Final answer:
The tendons of extensor pollicis longus and brevis are clinically significant because they are commonly associated with De Quervain's tenosynovitis.
Step-by-step explanation:
The tendons of extensor pollicis longus and brevis are clinically significant because they are commonly associated with a condition called De Quervain's tenosynovitis.
This condition is characterized by inflammation of the tendon sheaths in the thumb area, causing pain and difficulty with thumb movement.
De Quervain's tenosynovitis is often caused by repetitive thumb motions and can be treated with rest, immobilization, and anti-inflammatory medications.