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What are the major extra-renal manifestations of APKD?

a) Liver cysts and mitral valve prolapse
b) Pancreatic cysts and aortic dissection
c) Brain aneurysms and colonic diverticula
d) Spleen cysts and coronary artery disease

User Azazul
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1 Answer

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Final answer:

Autosomal Dominant Polycystic Kidney Disease can lead to major extra-renal manifestations such as liver cysts and cerebral aneurysms, as well as other complications like mitral valve prolapse and cardiac abnormalities.

Step-by-step explanation:

The major extra-renal manifestations of Autosomal Dominant Polycystic Kidney Disease (ADPKD) include liver cysts and cerebral aneurysms. Liver cysts are a common non-kidney manifestation of ADPKD, which can sometimes lead to hepatic fibrosis or other complications. On the other hand, cerebral aneurysms, particularly in the brain's blood vessels, can be a life-threatening condition due to the risk of bleeding if they rupture. Other possible manifestations include mitral valve prolapse, colonic diverticula, and cardiac abnormalities.

User Yetunde
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