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What is the best way to assess liver function in CHRONIC hepatitis?

a) Serum albumin level
b) Prothrombin time (INR)
c) Serum bilirubin level
d) Serum transaminases (AST and ALT) levels

1 Answer

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Final answer:

The best way to assess liver function in chronic hepatitis is through a combination of tests including Prothrombin time (INR), Serum albumin levels, Serum bilirubin levels, and Serum transaminases (AST and ALT) levels, as these provide a comprehensive overview of the liver's health and functionality.

Step-by-step explanation:

The best way to assess liver function in chronic hepatitis involves a combination of tests, as no single test can provide a complete picture. However, each marker can give important information about liver health. Prothrombin time (INR) is a significant indicator, as the liver is responsible for the production of coagulation factors, and an increased INR suggests a longer time for blood to clot, indicating liver dysfunction. Serum albumin levels reflect the liver's ability to synthesize proteins, which can decrease in chronic liver disease. Serum bilirubin levels indicate the liver's ability to process waste products, with elevated levels pointing to liver dysfunction. Lastly, serum transaminases (AST and ALT) levels rise dramatically in acute liver damage but can also provide insight into liver inflammation in chronic conditions.

For a holistic assessment of liver function in chronic hepatitis, healthcare professionals often consider a combination of these tests rather than relying on a single test.

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