Final answer:
The best non-invasive measure to use for acute exacerbation of COPD is oxygen therapy.
Step-by-step explanation:
The best non-invasive measure to use for acute exacerbation of COPD is Oxygen therapy. Oxygen therapy involves providing supplemental oxygen to patients to help improve their breathing and reduce symptoms such as shortness of breath and low oxygen levels in the blood.
In acute exacerbation of COPD, the airways become inflamed and narrow, making it difficult for air to flow in and out of the lungs. Oxygen therapy can help to improve the supply of oxygen to the body and reduce the workload on the lungs, allowing them to function more efficiently.
Other options listed in the question, such as antibiotics, surgery, and pain medication, may be used in specific situations, but they are not considered the first-line treatment for acute exacerbation of COPD.