Final answer:
Prolonged use of first-generation antipsychotics (FGAs) can cause side effects such as extrapyramidal symptoms, anticholinergic effects, and tardive dyskinesia.
Step-by-step explanation:
After prolonged use of first-generation antipsychotics (FGAs), several side effects can occur. These can include extrapyramidal symptoms (EPS) like tremors, rigidity, and bradykinesia. Additionally, FGAs may also cause symptoms such as dry mouth, blurred vision, constipation, and urinary retention due to their anticholinergic effects. Moreover, long-term use of FGAs may lead to a condition called tardive dyskinesia, characterized by repetitive and involuntary movements of the face, tongue, and limbs.