Final answer:
Hansten and Horn's Drug Interactions is accessed through an online database or in print, and it's crucial for healthcare professionals to manage drug-drug interactions. It aligns with modern drug discovery practices, where early interaction assessments are essential.
Step-by-step explanation:
Hansten and Horn's Drug Interactions is a comprehensive resource available for healthcare professionals to evaluate potential drug-drug interactions. This reference helps in assessing the clinical significance of interactions and provides guidance on how to manage them. Typically, the information can be accessed through a dedicated online platform or database, or in print form as a reference book.
Modern drug discovery often involves evaluating interactions early on, using in vitro assays to predict metabolism-related interactions, as described by Lee et al. (2011), and in vivo pharmacokinetic approaches to optimize drug development, as Li et al. (2013) suggest. Having access to resources like Hansten and Horn's can aid in addressing the complexities identified during drug development.