Final answer:
Long-acting injectable (LAI) antipsychotic medications include Risperdal Consta, Invega Sustenna/Trinza, Zyprexa Relprevv, Abilify Maintena/Aristada, and Haloperidol decanoate. These medications are used for the treatment of schizophrenia and other psychotic disorders, and their LAI formulations improve patient compliance.
Step-by-step explanation:
List of Long-acting Injectable Antipsychotic Formulations
Long-acting injectable (LAI) antipsychotic medications are used primarily for the treatment of schizophrenia and other psychotic disorders. These formulations are designed to provide a sustained release of medication, reducing the need for daily dosing and helping to improve compliance. Some commonly used LAI antipsychotics include:
- Risperidone (brand name: Risperdal Consta)
- Paliperidone palmitate (brand name: Invega Sustenna / Invega Trinza)
- Olanzapine pamoate (brand name: Zyprexa Relprevv)
- Aripiprazole (brand names: Abilify Maintena / Aristada)
- Haloperidol decanoate
These antipsychotics work by antagonizing various receptors in the brain, including dopamine (D2) and serotonin (5HT2) receptors. Some, like risperidone, also affect adrenergic and histaminergic receptors. They are effective in reducing symptoms such as hallucinations, delusions, and disordered thinking, and in managing aggressive and impulsive behavior.