Final answer:
The dopamine hypothesis suggests excessive dopamine activity in schizophrenia, while the glutamate hypothesis proposes abnormalities in the glutamate system. These hypotheses help us understand the underlying mechanisms of these disorders.
Step-by-step explanation:
The question is about the dopamine hypothesis and the glutamate hypothesis in schizophrenia. The dopamine hypothesis suggests that excessive dopamine activity in the brain leads to schizophrenia symptoms. On the other hand, the glutamate hypothesis proposes that abnormalities in the glutamate system contribute to the development of schizophrenia.
In Parkinson's disease, the neurodegeneration of dopaminergic neurons is associated with persistent glutamatergic stimulation. In schizophrenia, glutamatergic impairment and excitotoxic effects are observed. These hypotheses help us understand the underlying mechanisms of these disorders.
Keywords: dopamine hypothesis, glutamate hypothesis, schizophrenia, Parkinson's disease, neurodegeneration, glutamatergic impairment