Final answer:
An adverse response to isoniazid, indicated by yellowing of the sclera, suggests possible hepatotoxicity, which requires careful monitoring for liver damage.
Step-by-step explanation:
The client receiving isoniazid for tuberculosis may display signs of adverse reactions such as hepatotoxicity, neurotoxicity, and hematologic toxicity. Among the options given, D. Yellowing of the sclera would be indicative of possible hepatotoxicity, a known side effect of isoniazid. Careful monitoring for signs of liver damage, such as jaundice, which is characterized by the yellowing of the skin and sclera, is crucial during treatment with this medication.
The assessment finding that would indicate a possible adverse response to isoniazid for tuberculosis (TB) is tingling in extremities. Isoniazid can cause neurotoxicity as a side effect, which can manifest as tingling or numbness in the extremities.