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A nurse is educating a client with diabetes type 2 about newly prescribed glipizide. Which statement by the nurse best describes the action of glipizide?

"This medication absorbs the excess carbohydrates from your intestinal tract."

"This medication will inhibit the release of glucose stored in the liver."

"This medication will stimulate your pancreas to release insulin."

"This medication works by increasing the ability of the cells to uptake glucose."

1 Answer

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Final answer:

The statement by the nurse that best describes the action of glipizide for a client with type 2 diabetes is that it stimulates the pancreas to release insulin. Glipizide, a sulfonylurea drug, helps to lower blood glucose by increasing insulin secretion, leading to greater glucose uptake by muscle and adipose cells.

Step-by-step explanation:

The nurse educating a client with type 2 diabetes about the action of glipizide would provide the most accurate description by stating: "This medication will stimulate your pancreas to release insulin." Glipizide is a member of the sulfonylurea class of medications, which functions primarily by stimulating the beta cells of the pancreas to secrete more insulin. Insulin is crucial for controlling blood glucose levels by increasing the uptake of glucose into the body's cells, particularly the muscle and adipose cells, thereby reducing blood glucose concentration back to homeostasis. This increased uptake of glucose supports its storage as glycogen in the liver and muscle and its conversion to energy (ATP) by cells throughout the body.

Hypoglycemia is a potential side effect due to the increased insulin and subsequent lowering of blood glucose, and patients must be monitored for symptoms such as hunger, sweatiness, shakiness, and weakness. Any occurrence of these symptoms should be addressed immediately as they signal dangerously low blood glucose levels. Proper understanding of drug mechanism and its effects, including potential side effects like hypoglycemia, is crucial for the safe management of type 2 diabetes.

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