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Takayasu arteritis

a•Takayasu arteritis is a chronic vasculitis of unknown etiology affecting primarily the (1). The inflammation may be localized or may involve the entire vessel.
b•The initial vascular lesions frequently occur in the middle or proximal (2). As the disease progresses, the carotids, vertebrals, brachiocephalic, right middle or proximal subclavian artery, and aorta may also be affected.
c•The (3) and (4) are involved in approximately 50% of patients. The inflammatory process causes thickening of the walls of the affected arteries or involved segment of the aorta.
d•The proximal aorta may become (5) secondary to inflammatory injury. (6) may be present and is usually caused by dilatation of the (7).

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Final answer:

Takayasu arteritis is a chronic vasculitis that primarily affects large arteries, causing thickening of arterial walls. Treatment may include medication and surgical interventions.

Step-by-step explanation:

Takayasu arteritis is a chronic vasculitis of unknown etiology that primarily affects the large arteries, such as the aorta and its branches. The inflammation can involve the entire vessel, causing thickening of the arterial walls. This condition commonly affects the carotid arteries and subclavian arteries.

The disease progression can lead to stenosis or obliteration of the affected arteries, resulting in reduced blood flow to various organs. Symptoms may include hypertension, decreased pulse, and symptoms related to inadequate blood supply to specific organs.

Treatment for Takayasu arteritis may include medications to suppress inflammation, such as corticosteroids and immunosuppressants. In some cases, surgical interventions like angioplasty with a balloon catheter or bypass procedures may be necessary to restore blood flow. Regular follow-up and medication management are important for long-term management of the disease.

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