Final answer:
Alpha1 activation has clinical consequences such as decreased smooth muscle motility in the gastrointestinal tract, vasoconstriction in blood vessels, and other effects on glycogenolysis and sodium reabsorption.
Step-by-step explanation:
When alpha1-adrenergic receptors are activated, it leads to various clinical consequences. One of the consequences is a decrease in the motility of smooth muscles in the gastrointestinal tract. This means that the muscles in the digestive system become less active, which can result in slower digestion.
Additionally, alpha1 activation causes vasoconstriction in many blood vessels, including those in the skin, gastrointestinal system, kidney, and brain. This narrowing of blood vessels can lead to increased blood pressure and reduced blood flow to certain areas of the body.
Other effects of alpha1 activation include glycogenolysis and gluconeogenesis, secretion from sweat glands, and increased sodium reabsorption from the kidney.