Final answer:
The clinical consequences of beta1 activation include an increase in cardiac output and blood pressure. Beta blockers can be prescribed to slow down the heart rate, but overprescription may lead to bradycardia and heart stoppage. Beta1 activation also affects the circulatory system through vasoconstriction and heart muscle contraction.
Step-by-step explanation:
The clinical consequences of beta1 activation include an increase in cardiac output. This is achieved by raising heart rate and increasing the volume expelled with each beat, also known as the ejection fraction.
Due to the activation of beta1 receptors, certain medications known as beta blockers, which inhibit these receptors, are used to slow down the heart rate and can be prescribed to treat hypertension. However, overprescription of these drugs may lead to bradycardia and even heart stoppage.
Beta1 activation also has direct effects on the circulatory system. It causes arteries to constrict, resulting in an increase in blood pressure and volume. Additionally, it increases heart muscle contraction, promotes smooth muscle relaxation, and stimulates glycogenolysis.