Final answer:
The trusted agents for issuing and ensuring member notification for urine sample testing are typically appointed by the employer or organization conducting the testing.
Step-by-step explanation:
In the context of urine sample testing, the trusted agents who are responsible for issuing and ensuring member notification can vary depending on the specific situation. However, in many cases, it is the employer or organization conducting the testing that appoints the trusted agents. These agents may include medical professionals, such as doctors or nurses, who are trained and authorized to collect urine samples and ensure the proper notification process.