Question

Although ____________ (type I hypersensitivity reaction) is rare (approximately 1-5 per 10,000 vaccinations), it may manifest as vomiting, diarrhea, respiratory distress, facial or generalized pruritus, facial swelling, and collapse.

Answer 1

Anaphylaxis is a rare but serious type I hypersensitivity reaction that can be life-threatening, characterized by symptoms such as facial swelling, difficulty breathing, and a precipitous drop in blood pressure.

Step-by-step explanation:

Although anaphylaxis (type I hypersensitivity reaction) is rare (approximately 1-5 per 10,000 vaccinations), it may manifest as vomiting, diarrhea, respiratory distress, facial or generalized pruritus, facial swelling, and collapse.Anaphylaxis is a severe and life-threatening systemic type I hypersensitivity reaction that occurs upon exposure to an allergen in a sensitized individual. This condition involves immunoglobulin E (IgE) and mast cell degranulation, leading to a swift immune response.

Symptoms of anaphylaxis may include extensive facial swelling, breathing difficulties due to a swollen tongue and trachea, a dramatic drop in blood pressure, and potential shock. Without immediate treatment, such as the administration of epinephrine, anaphylaxis can be fatal within minutes. Apart from systemic reactions like anaphylaxis, type I hypersensitivity can also cause localized symptoms such as hay fever, hives, or asthma.