Final answer:
Infusing vesicant drugs peripherally should avoid the hand and wrist due to the risk of severe tissue damage, including inflammation, edema, and necrosis, as these areas have superficial veins that are more vulnerable to complications.
Step-by-step explanation:
The infusion of vesicant drugs into the peripheral veins should avoid areas like the back of the hand and wrist due to the higher risk of complications such as extravasation, which can cause severe tissue damage if the drug leaks into the surrounding tissue. The back of the hand and wrist have superficial veins that are not well protected by muscle and connective tissue, increasing the likelihood of extravasation. Furthermore, these areas have a higher density of joints, nerves, and tendons, which are more susceptible to injury from vesicants.
The administration of vesicants in such locations can result in inflammation, swelling, blistering, and tissue necrosis, which can lead to long-term functional impairment, infection, and even the need for surgical intervention to address the damage.
Infiltration of vesicant drugs in the hand or wrist can also interfere with the patient’s ability to perform daily activities and occupational functions due to the complexity of movements required by these parts of the body. Edema and compression of nerves can lead to significant discomfort and mobility issues.