Final answer:
D "This combination medication will better help to manage your pain." The nurse should inform the client that acetaminophen with codeine is a combination medication that will help to manage their pain.
Step-by-step explanation:
The correct response by the nurse to the client's question would be option D: "This combination medication will better help to manage your pain." Acetaminophen with codeine is a combination medication that is typically prescribed for mild to moderate pain relief. Acetaminophen is a non-opioid pain reliever that helps to reduce inflammation and fever, while codeine is an opioid that works by binding to opioid receptors in the brain and spinal cord, providing pain relief.