Final answer:
The nurse should reinforce that levothyroxine should be taken in the morning.
Step-by-step explanation:
The nurse should make sure to reinforce the information that levothyroxine should be taken in the morning. Levothyroxine is a thyroid hormone replacement medication used to treat hypothyroidism. It is typically taken on an empty stomach in the morning, at least 30 minutes before eating, as food can interfere with its absorption and effectiveness.